1. Rudolph L. Leibel, MD

    • Department of Pediatrics
      Division of Pediatric Molecular Genetics
    • Department of Medicine
      Division of Endocrinology

    Dr. Leibel's research focuses on the genetics of obesity and noninsulin-dependent diabetes. His laboratory has mapped, cloned, and identified mutations in the obese and fatty genes in rats, mice, and, more recently, in humans. The obese gene encodes leptin, an adipose derived hormone responsible for regulating body weight, whereas the fatty gene encodes the leptin receptor. Currently, his research group is defining the physiological bases by which this and related signaling networks regulate body size and composition. For example, changes in leptin production following reduction in body fat might play a role in the metabolic changes that accompany weight loss in humans. Dr. Leibel's laboratory is also working to isolate additional rodent genes that influence body weight and the susceptibility to noninsulin dependent diabetes mellitus in the context of obesity. Laboratory members have extended their genetic studies to search for similar obesity and diabetes related genes in human families.

    CUMC crown logoRudolph L. Leibel, MD
    is accepting new patients.
    Call (212) 851-5315 for appointments.

    Provider Information

    Board Certifications

    • Pediatrics

    Areas of Expertise

    • Obesity
    • Clinical Molecular Genetics

    Primary Location

    • Russ Berrie Medical Science Pavilion

      1150 St. Nicholas Avenue
      Floor: 6
      New York, NY 10032
      (212) 851-5315
      (212) 851-5315

    Insurance Programs

    Please contact the provider’s office directly to verify that your particular insurance is accepted.
    • Medicare [Medicare] - Open

    Biographical Detail

    Academic Appointments

    • Professor of Medicine
    • Professor of Pediatrics

    Current Administrative Positions

    • Co-Director, Naomi Berrie Diabetes Center

    Education And Training

      Education & Training

    • Albert Einstein College of Medicine - Yeshiva University
    • Internship: Massachusetts General Hospital
    • Residency: Massachusetts General Hospital
    • Residency: Children's Hospital of Boston
    • Fellowship: Massachusetts General Hospital



    Languages Spoken

    • English
  2. Genetics of obesity and noninsulin-dependent diabetes

    Research Information

    NIH Grants

  3. publications

    For a complete list of publications, please visit PubMed.gov