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Andrew F. Teich, MD

Board Certifications: 
Anatomic Pathology, Neuropathology
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Credentials & Experience

Board Certifications

  • Anatomic Pathology
  • Neuropathology

Specialties

Education & Training

  • Columbia University College of Physicians and Surgeons
  • Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
  • Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center

Honors & Awards

 2016    Paul B. Beeson Emerging Leaders Career Development Award in Aging, NIH-NIA

           2014    Margaret M. Cahn Research Award, Alzheimer’s Association

           2011    Louis V. Gerstner, Jr. Scholar Award,  Louis V. Gerstner, Jr. Scholar Foundation/Columbia University

About Andrew Teich

Academic Titles

  • Assistant Professor of Pathology & Cell Biology

Administrative Positions

  • Co-Director New York Brain Bank

Hospital Affiliations

  • NewYork-Presbyterian/Columbia

Gender

  • Male

Insurance Accepted

Aetna

  • EPO
  • HMO
  • Medicare Managed Care
  • NY Signature
  • POS
  • PPO
  • Signature Administrators
  • Student Health

Cigna

  • EPO
  • Great West
  • HMO
  • POS
  • PPO

Emblem/GHI

  • HMO
  • Medicare Managed Care
  • PPO

Emblem/HIP

  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicaid Managed Care
  • Medicare Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Empire Blue Cross Blue Shield

  • Blue Priority
  • EPO
  • HMO
  • Medicare (Mediblue)
  • NYP Employee Plan
  • Pathway (Exchange)
  • POS
  • PPO

Local 1199

  • Local 1199

MagnaCare

  • MagnaCare

Multiplan

  • Multiplan

Oxford Health Plans

  • Freedom
  • Liberty
  • Medicare Managed Care

POMCO

  • POMCO

UnitedHealthcare

  • Columbia University Employee Plan
  • Compass (Exchange)
  • EPO
  • Essential Plan
  • HMO
  • Medicaid (Community Plan)
  • Medicare Managed Care
  • POS
  • PPO

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Research

Our research focuses on how synaptic plasticity is impaired in neurodegenerative disease, with an emphasis on Alzheimer's disease. We are interested both in studying mechanisms of synaptic dysfunction as well as in identifying targets for therapeutic intervention. Specific issues we are currently focused on are:

1) I am interested in what beta-amyloid is normally doing in the brains of people without Alzheimer's disease. Beta-amyloid is present at low levels in the brain throughout life, and may have an important role in normal brain physiology. Ironically, there is some evidence that beta-amyloid actually facilitates neuronal connectivity and memory in people when it is present at low (normal) concentrations, and becomes toxic to neurons at higher concentrations. By studying its normal function and how it is regulated, we hope to understand better how it may accumulate in the brains of Alzheimer's patients.

2) We are using computational techniques to analyze genome expression data from neurons of Alzheimer's patients to determine whether there are any transcription factors that are primarily responsible for driving synaptic dysfunction in Alzheimer's disease. Transcription factors identified through this effort will be further studied as possible targets for therapeutic intervention.

Grants

A SYSTEMS APPROACH TO DNA METHYLATION, GENE EXPRESSION, AND COGNITIVE DYSFUNCTION IN ALZHEIMER S DISEASE (Federal Gov)

May 1 2015 - Jan 31 2020

AN INTEGRATIVE ANALYSIS OF DNA METHYLATION, TRANSCRIPTOMIC CHANGES, AND COGNITIVE DYSFUNCTION IN ALZHEIMER S DISEASE (Federal Gov)

Sep 30 2016 - May 31 2019

A CROSS-SPECIES STUDY OF DNA METHYLATION IN ALZHEIMER S DISEASE DEMENTIA (Private)

Jun 1 2016 - May 31 2018

A STUDY OF ZCCHC17 REGULATION OF SYNAPTIC GENES IN ALZHEIMERS DISEASE (Federal Gov)

Sep 1 2014 - May 31 2017

A THERAPEUTIC APPROACH TO SYNAPTIC DYSFUNCTION IN ALZHEIMER S DISEASE (Private)

Jan 1 2014 - Dec 31 2015

ALZHEIMER S DISEASE RESEARCH CENTER AT COLUMBIA UNIVERSITY (Federal Gov)

Jun 1 2010 - May 31 2015

BETA-AMYLOID42 POSITIVELY REGULATES ALPHA7-CHOLINERGIC RECEPTORS (Private)

Sep 1 2011 - Aug 31 2013

Selected Publications

  1. Peter Koppensteiner, Fabrizio Trinchese, Mauro Fà, Daniela Puzzo, Walter Gulisano, Shijun Yan, Arthur Poussin, Shumin Liu, Ian Orozco, Elena Dale, Andrew F. Teich, Agostino Palmeri, Ipe Ninan, Stefan Boehm & Ottavio Arancio. Scientific Reports, 2016 Sep 1;6:32553. doi: 10.1038/srep32553.
  2. M. Fá, D. Puzzo, R. Piacentini, A. Staniszewski, H. Zhang, M. A. Baltrons, D. D. Li Puma, I. Chatterjee, J. Li1, F. Saeed, H. L. Berman, C. Ripoli, W. Gulisano, J. Gonzalez, H. Tian, J. A. Costa, P. Lopez, E. Davidowitz, W. H. Yu, V. Haroutunian, L. M. Brown, A. Palmeri, E. M. Sigurdsson, K. E. Duff, A. F. Teich, L. S. Honig, M. Sierks, J. G. Moe, L. D’Adamio, C. Grassi, N. M. Kanaan, P. E. Fraser & O. Arancio. Extracellular Tau Oligomers Produce an Immediate Impairment of LTP and Memory. Scientific Reports, 2016 Jan 20;6:19393.
  3. A. F. Teich, Sakurai M., Patel M., Holman C., Saeed F., Fiorito J., Arancio O. PDE5 Exists in Human Neurons and is a Viable Therapeutic Target for Neurologic Disease. Journal of Alzheimer’s Disease, 2016 9;52(1): 295-302.
  4. Gill BJ, Pisapia DJ, Malone HR, Goldstein H, Lei L, Sonabend A, Yun J, Samanamud J, Sims JS, Banu M, Dovas A, Teich AF, Sheth SA, McKhann GM, Sisti MB, Bruce JN, Sims PA, Canoll P. MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. (2014)26;111(34):12550-5.
  5. Teich AF, Patel M, Arancio O. A Reliable Way to Detect Endogenous Murine β-Amyloid. PLoSOne. (2013) 8(2):e55647.
  6. Teich AF and Qian N. V1 orientation plasticity is explained by broadly tuned feedforward inputs and intracortical sharpening. Visual Neuroscience 27:57-73, 2010.
  7. Teich AF and Qian N. Comparison Among Some Models of V1 Orientation Selectivity. Journal of Neurophysiology 96:404-419, 2006.
  8. Teich AF and Qian N. Learning and adaptation in a recurrent model of V1 orientation selectivity. Journal of Neurophysiology 89:2086-2100, 2003.