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Daniel E Freedberg, MD

Board Certifications: 
Gastroenterology, Internal Medicine
Accepting New Patients
Virtual Visits/Telehealth
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Credentials & Experience

Board Certifications

  • Gastroenterology
  • Internal Medicine

Clinical Expertise

  • Digestive System Disorder
  • Gastroenterology
  • Gastrointestinal Disease
  • GERD (Gastroesophageal Reflux Disease)

Education & Training

  • MD, 2008 Harvard Medical School
  • Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
  • Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center

About Daniel Freedberg

Dr. Freedberg graduated from Harvard Medical School and completed his residency and fellowship training at Columbia University. He received a Master's degree in biostatistics from Columbia's Mailman School of Public Health. Dr. Freedberg's research focuses on the use of acid suppression medications, Clostridium difficile infection, and the gastrointestinal microbiome. Current projects include studies of how acid suppression medications alter the colonic microbiome and of how alterations in the gastrointestinal flora predispose patients to Clostridium difficile and other infections during periods of critical illness. His research is funded by the National Institutes of Health and the American Gastroenterological Association.

Academic Titles

  • Assistant Professor Medicine and Epidemiology

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center
  • NewYork-Presbyterian Allen Hospital

Gender

  • Male

Insurance Accepted

Aetna

  • Aetna Signature Administrators
  • EPO
  • HMO
  • Medicare Managed Care
  • NYP Employee Plan
  • NY Signature
  • POS
  • PPO
  • Student Health

Affinity Health Plan

  • Essential Plan
  • Medicaid Managed Care

AgeWell

  • Medicare Managed Care
  • Special Needs

Amida Care

  • Special Needs

Capital District Physician Health Plan

  • Capital District Physician Health Plan

Cigna

  • EPO
  • Great West (National)
  • HMO
  • POS
  • PPO

Emblem/GHI

  • Medicare Managed Care
  • PPO

Empire Blue Cross/Blue Shield

  • EPO
  • Medicare Managed Care
  • PPO

Fidelis Care

  • Child/Family Health Plus
  • Medicaid Managed Care
  • Medicare Managed Care

Health First

  • Child/Family Health Plus
  • Leaf (Exchange)
  • Medicaid Managed Care
  • Medicare Managed Care

Health Insurance Plan of NY (HIP)

  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicaid Managed Care
  • Medicare Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Health Plus - Amerigroup

  • Child/Family Health Plus
  • Essential Plan
  • Medicaid Managed Care

Local 1199

  • Local 1199

MagnaCare (National)

  • MagnaCare

Medicare

  • Traditional Medicare

Multiplan

  • Multiplan

MVP Health Care

  • Child/Family Health Plus
  • Essential Plan
  • HMO
  • Medicaid Managed Care

Oxford Health Plans

  • Freedom
  • Liberty

United Health Care

  • Columbia Employee POS
  • Compass (Exchange)
  • HMO
  • Medicaid (Community Plan)
  • Medicare Managed Care
  • POS
  • PPO

VNSNY CHOICE SelectHealth

  • Medicare Managed Care
  • Select Health
  • Special Needs

WellCare

  • Medicaid Managed Care
  • Medicare Managed Care

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Contact & Locations

Research

I am a clinical and translational investigator focused on enteric infections and the gastrointestinal microbiome in the setting of critical illness. I have experience in molecular laboratory research, clinical training as a physician, a dual appointment in Medicine and Epidemiology, and am the recipient of several grants supporting ICU-based human subjects research focused around enteric colonization in the ICU. With funding from the NIH, the American Gastroenterological Association (AGA), and the Department of Defense, I have built large ICU patient cohorts containing longitudinal clinical data, serial rectal swabs, whole stools, and other bio-samples. These data have allowed us to interrogate the dynamic changes that take place within the gastrointestinal microbiome during critical illness and to ask how these changes may impact risk for ICU-acquired infections. Our preliminary studies show that colonizing enteric organisms such as vancomycin-resistant Enterococcus (VRE) are important determinants of patients’ subsequent risk for infection. We have also found that colonizing enteric organisms can change health outcomes for patients who share the same hospital environment, even if these neighboring patients are not themselves colonized. The normal native microbiota resists colonization with VRE, C. difficile, and similar multidrug-resistant or antibiotic-associated organisms, and a major focus of our current work is how to augment enteric colonization resistance in the face of ICU antibiotics.

Selected Publications

  • Wang Y, Schluger A, Li J, Gomez-Simmonds A. Salmasian H, Freedberg D. Does addition of intravenous metronidazole to oral vancomycin improve outcomes in clostridioides difficile infection? Clin Infect Dis. 2019 pii: ciz1115. doi: 10.1093/cid/ciz1115. PMID: 31714955

  • Freedberg DE, Zhou MJ, Cohen ME, Annavajhala MK, Khan S, Moscoso DI, Brooks C, Whittier S, Chong DH, Uhlemann AC, Abrams JA. Pathogen colonization of the gastrointestinal microbiome at intensive care unit admission and risk for subsequent death or infection. Intensive Care Med. 2018; 44(8):1203-1211. PMID: 29936583

  • Seeley JJ, Baker RG, Mohamed G, Bruns T, Hayden MS, Deshmukh SD, Freedberg DE, Ghosh S. Induction of innate immune memory via microRNA targeting of chromatin remodelling factors. Nature. 2018; 559(7712):114-119. PMID: 29950719