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James M. Noble, MD, MS

Board Certifications: 
Accepting New Patients
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Phone Appointments

New and Existing Patients: 
(212) 305-6939


For existing patients, login to make an appointment, view documentation or contact your care provider.

Credentials & Experience

Board Certifications

  • Neurology

Clinical Expertise

  • Alzheimer's Disease
  • Neurobehavioral Syndrome
  • Neurobehavioral Disorders
  • Concussion
  • Dementia
  • Behavioral Disorder
  • Memory Disorder


Education & Training

  • Emory University School of Medicine
  • Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
  • Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center

Honors & Awards

  • 2012 Selection, Emerging Leaders Forum, American Academy of Neurology 
  • 2012 Virginia Apgar Teaching Academy Scholar, Columbia University College of Physicians and Surgeons
  • 2011 Stephen Q. Shafer Award for Humanism in Neurology, Columbia University Medical Center 
  • 2008 Anna C. Gelman Award for Excellence in Epidemiology, Mailman School of Public Health, Columbia University  

About James Noble

Dr. Noble completed his undergraduate studies in math and chemistry at Vanderbilt University, followed by medical school at Emory University. His graduate medical training included internal medicine internship, neurology residency including chief resident in neurology, and neuroepidemiology and behavioral neurology fellowship, all at Columbia University Medical Center. Accordingly, he is board certified in neurology, behavioral neurology & neuropsychiatry, and public health.

Dr. Noble primarily sees patients with dementia but also leads Team Concussion, focusing on sports-related concussion care, and sees patients in a general neurology practice. Dr. Noble is fluent in Spanish and his comprehensive approach to care views the patient within the entire family dynamic, with particular focus on disadvantaged communities.

His professional leadership has been recognized by the American Academy of Neurology, which has selected him to the Emerging Leaders Forum. Dr. Noble is recognized as a leader in neurologic education at Columbia University College of Physicians and Surgeons, as its clerkship director and a scholar in the Virginia Apgar Teaching Academy. Dr. Noble is also the president of Arts & Minds, a non-profit organization promoting well-being for dementia patients and their caregivers via art-centered experiences.

Academic Titles

  • Assistant Professor of Neurology (in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain) at CUMC

Administrative Positions

  • Director, Neurology Clerkship
  • Director, Concussion and Sports-Related Head Injury Program

Hospital Affiliations

  • NewYork-Presbyterian/Columbia


  • Spanish


  • Male

Insurance Accepted


  • EPO
  • HMO
  • Medicare Managed Care
  • NY Signature
  • POS
  • PPO
  • Signature Administrators
  • Student Health


  • Access (Exchange)
  • Essential Plan
  • Medicaid Managed Care

Amida Care

  • Special Needs Plan


  • EPO
  • Great West
  • HMO
  • POS
  • PPO


  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicaid Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Empire Blue Cross Blue Shield

  • Blue Priority
  • EPO
  • HMO
  • Medicare (Mediblue)
  • NYP Employee Plan
  • Pathway (Exchange)
  • POS
  • PPO

Empire Blue Cross Blue Shield HealthPlus

  • Child/Family Health Plus
  • Essential Plan
  • Medicaid Managed Care

Fidelis Care

  • Child/Family Health Plus
  • Medicaid Managed Care


  • Child/Family Health Plus
  • Medicaid Managed Care

Local 1199




Oxford Health Plans

  • Freedom
  • Liberty



  • Columbia University Employee Plan
  • EPO
  • HMO
  • Medicaid (Community Plan)
  • POS
  • PPO


  • SelectHealth

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Contact & Locations

710 West 168th Street
New York, New York 10032
Phone: (212) 305-6939
(212) 305-1145


In addition to patient care, Dr. Noble’s research interests include health literacy, systemic inflammatory markers as contributors to stroke and dementia health disparities, the role of cognitively stimulating activities in dementia care, and sports-related concussion.

Research Interests

  • Health literacy
  • Alzheimer disease
  • Chronic traumatic encephalopathy
  • Dementia
  • Lewy Body Disease
  • Frontotemporal dementia
  • Vascular dementia
  • Post-concussion syndrome


NIA T35 AG044303-01: The BRAIN (Brief Research in Aging and Interdisciplinary Neurosciences) Project, as co-Principal Investigator

NIH-NIDCR R56 DE022568-01A1 Periodontal Exposure and Risk of Incident Dementia in the Washington Heights Inwood Columbia Aging Project (WHICAP-PERIoD)

NINDS R01 NS067443-01A1: RCT: Effect of Novel Intervention to Improve Stroke Symptom Recognition, as Co-Investigator


Mar 1 2016 - Feb 28 2021


Jul 1 2014 - Dec 31 2019


Jul 1 2016 - Feb 28 2017


Sep 17 2013 - Aug 31 2016


Sep 30 2012 - Aug 31 2016


Jan 1 2012 - Mar 31 2013


Sep 1 2008 - Jun 30 2011


Jul 1 2005 - Jun 30 2008

Selected Publications

Original Peer Reviewed Articles:

Williams O, Noble JM. "Hip-Hop" Stroke: A Stroke Educational Program for Elementary School Children Living in a High-Risk Community. Stroke. 2008; 39:2809-2816

Noble JM, Borrell LN, Papapanou PN, Elkind M, Scarmeas N, Wright C. Association of the Periodontitis Pathogen Porphyromonas gingivalis with Poor Memory: Analysis of the Third National Health and Nutrition Examination Survey (NHANES-III). J Neurol Neurosurg Psychiatr 2009 Nov;80(11):1206-11

Noble JM, Manly JJ, Schupf N, Tang MX, Mayeux R, Luchsinger JA. Association of C-reactive protein with cognitive impairment. Arch Neurol. 2010 Jan;67(1):87-92.

Cheng D, Noble JM, Tang MX, Schupf N, Mayeux R, Luchsinger, JA. Type 2 Diabetes and Late Onset Alzheimer’s Disease. Dement Geriatr Cogn Disord 2011;31:424–430

Noble JM, Manly JJ, Schupf N, Tang M-X, Luchsinger JA. Type 2 diabetes and ethnic disparities in cognitive impairment. Ethnicity and Disease 2012; 1: 38-44.

Williams O, DeSorbo A, Noble JM, Gerin W. Child-Mediated Stroke Communication: Findings from Hip Hop Stroke. Stroke 2012 Jan;43(1):163-9.

Williams OA, DeSorbo AL, Noble JM, Shaffer M, Gerin W. Long-term learning of stroke knowledge among children in a high-risk community. Neurology 2012 Aug 21;79(8):802-6

DeSorbo A, Noble J, Shaffer M, Gerin W, Williams O. The Use of an Audience Response System in an Elementary School-Based Health Education Program. Health Education and Behavior.  2013 Oct;40(5):531-5.

Williams O, Hecht MF, Desorbo AL, Huq S, Noble JM. Effect of a Novel Video Game on Stroke Knowledge of 9- to 10-Year-Old, Low-Income Children. Stroke. 2014 Jan 30 [epub ahead of print]

Noble JM, Hedmann MG, Williams O. Improving dementia health literacy using the FLOW mnemonic: pilot findings from the Old S.C.H.O.O.L. Hip Hop Program. Health Education & Behavior (in press)

Case Reports:

*Noble JM, Canoll P, Honig LS. Brain Tumor-Associated Dementia. Sci. Aging Knowl. Environ. 2005 Aug 24; 2005(34):dn2

*Noble JM, Anderson CT, Etienne M, Williams O, Adams DJ. Sarcoid meningitis with fulminant delirium and markedly abnormal cerebrospinal fluid. Arch Neurol 2007 Jan;64(1):129-31

Sommerville RB, Noble JM, Vonsattel JP, DeLaPaz R, Wright CB.  Eosinophilic Vasculitis in an Isolated CNS Distribution. J Neurol Neurosurg Psychiatry.2007;78:85-88.

*Noble JM, Mandel A, Patterson MC. Scurvy and Rickets Masked by Chronic Neurologic Illness: Revisiting “Psychologic Malnutrition.” Pediatrics. 2007 March;119(3):e783-90.

*Etienne M, Noble JM. Multiple parenchymal tuberculomas without tuberculous meningitis. Arch Neurol. 2007;64:1045-1047.


Luchsinger JA, Noble JM, Scarmeas N. Diet and Alzheimer's Disease. Curr Neurol Neurosci Rep. 2007 Sep;7(5):366-372.

*Noble JM, Patterson MC. “Vitamin C Deficiency,” invited review for BMJ Point of Care (BMJ Publishing Group), original publication 2008; updated 2009-12.

*Noble JM, Scarmeas N. Application of PET Imaging to Diagnosis of Alzheimer’s Disease and Mild Cognitive Impairment. Int Rev Neurobiol 2009;84C:133-149

Noble J, Scarmeas N, Papapanou PN. Poor oral health as a chronic, potentially modifiable dementia risk factor: review of the literature. Curr Neurol Neurosci Rep. 2013 Oct;13(10):384.

Noble J, Hesdorffer D. Sport-Related Concussions: A Review of Epidemiology, Challenges in Diagnosis, and Potential Risk Factors. Neuropscyhol Rev 2013 Dec;23(4):273-84.

*Noble JM, Weimer LH. Chronic complications of Alcohol Abuse. AAN Continuum. 2014 June (in preparation)

Book Chapters:

*Noble JM, Scarmeas N. “Cognitive impairment.” Improving Oral Health for the Elderly: An Interdisciplinary Approach. Eds. Ira B. Lamster, DDS, MMSc, and Mary E. Northridge, PhD, MPH. Springer US Books 2008.

*Noble JM, Scarmeas N. “Frontotemporal dementia” Merritt’s Neurology, 12th ed. Eds: Lewis P. Rowland and Timothy A. Pedley. LWW 2010.

Sevigny J, Frontera J, Noble JM. Viral Infections of the Nervous System, Current Diagnosis and Treatment in Neurology, 2nd ed. Ed: John CM Brust, Lange 2012.

Rippon G and Noble JM. “Parkinson Disease Dementia and Dementia with Lewy Bodies.” Current Diagnosis and Treatment in Neurology, 2nd ed. Ed: John CM Brust, Lange 2012.

Published Correspondence:

Noble JM, Hauser WA. [Correspondence to] Effects of rivastigmine on cognitive function in patients with traumatic brain injury. Neurology 2007 May 15;68(20):1749

Dhamoon M, Noble JM. [Correspondence to] Intranasal insulin improves cognition and modulates beta-amyloid in early AD.  Neurology. 2009 Jan 20;72(3):292-294.

Published Abstracts:

Williams O, Noble JM, Brust JCM. Recombinant Tissue Plasminogen Activator (rtPA) for Acute Ischemic Stroke among African Americans in Central Harlem. Annals of Neurology, 2005, 58 (S9), p S45

Williams O, Noble JM, Brust JCM. Stroke Associated with Cocaine Abuse: No Longer Just a Problem of the Young. Neurology. March 2006; 66 (Suppl 2): A384.

*Williams O, Noble JM. “Hip-Hop” Stroke Education in Central Harlem Elementary Schools: Pilot Data from a Novel Intervention and Proposed Educational Model for Stroke Awareness Developed by the National Stroke Association. Stroke 2007.38:457-8.

*Noble JM, Scarmeas N, Honig L. Challenges in dementia diagnosis in a multiethnic population. Neurology 2007; 68 Suppl 1:A237

*Noble JM, Manly JJ, Schupf N, Mayeux R, Luchsinger JA. Possible disparate contribution of diabetes to cognitive impairment in elderly minorities. Neuroepidemiology 2007; 28:125.

Williams O, Wowo B, Noble J, Brust J. Insurance Coverage And Ambulance Use During Acute Stroke In A Low Income Inner City Population. Stroke 2008; 39:627.

*Noble J, Borrell LN, Papapanou PN, Elkind M, Scarmeas N, Wright C. Association of the Periodontitis Pathogen Porphyromonas gingivalis with Poor Memory: Analysis of the Third National Health and Nutrition Examination Survey (NHANES-III). Neurology 2008; 70 Suppl 1: A191.

*Noble J, Schupf N, Luchsinger J. Relation of high sensitivity C-reactive protein with plasma amyloid beta. Neurology 2009; 72 Suppl 3: A53

Noble JM, Manly JJ, Schupf N, Tang MX, Mayeux R, Luchsinger JA. “Relation of C-reactive protein to cognitive impairment.” Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2009; 5(4S): P297

Luchsinger JA, Noble JM, Tang MX, Mayeux R. “Hyperinsulinemia, defined as low adiponectin or type 2 diabetes in the elderly, is related with higher late-onset Alzheimer's disease risk” Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2009; 5(4S): P386

Williams O, DeSorbo A, Noble JM. Lifetime Acquired Stroke Knowledge in a High Risk Community: Parents Versus Children. Annals of Neurology, 2010, 68 (S14), p S11

Williams OA, Gerin W, DeSorbo AL, Noble JM. “A Novel Interventional Strategy to Improve Stroke Awareness: The Hip Hop Stroke Project.” Psychosomatic Medicine 2011; 73 (3) A100.

Williams O, DeSorbo A, Noble J. Hip Hop Stroke: Long-Term Retention of Stroke Knowledge Among Sixth Graders Living in a Low-Income Neighborhood. Stroke 2012 43: A2476

Williams O, DeSorbo A, Noble J. Hip Hop Stroke: The Standalone Effect of Musical Cartoons on Stroke Knowledge of Fourth Grade Children Living in a Low-Income Neighborhood. Stroke 2012 43: A2476

Noble J, Scarmeas N, Celentia R, Elkind M, Wright C, Schupf N, Papapanou N. Serum Antibodies to Periodontal Pathogens are associated with Incident Alzheimer Disease. Alzheimer’s & Dementia 2012, 8(4), P498

Noble J, Kang M-S, Honig L. Arteriosclerosis and Alzheimer's disease: A case-control pathologic study. Alzheimer’s & Dementia 2012, 8(4), P298

Collins-Praino L, Scarmeas N, Manly J, Schupf N, Noble J, Provenzano F, Griffith E, DeCarli C, Mayeux R, Luchsinger J, Brickman A. White Matter Hyperintensities May Mediate the Relationship Between Inflammation and Cognition in an Elderly Cohort. Alzheimer’s & Dementia 2012, 8(4), P523

Shams T, Brickman AM, Gossett J, Levine W, Noble JM. Subtle Post-Concussion Cognitive Impairment Is Under-Recognized, and yet Identifiable: Findings from the Concussion in Columbia University Sports Student (ConCUSS) Study [ABSTRACT]  Ann Neurol Dec 2013: 74(S17); page S37.