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Medicine Reaction, Breast Problems

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Medicine Reaction, Breast Problems

Many prescription and nonprescription medicines can cause breast problems, such as breast tenderness or nipple discharge. A few examples are:

  • Some antidepressants.
  • Some blood pressure medicines.
  • Corticosteroids, such as prednisone.
  • Medicines that contain hormones, such as birth control pills, hormone therapy, and infertility medicines.
  • Migraine headache medicines, such as sumatriptan.

Cimetidine, such as Tagamet, may cause nipple discharge and breast enlargement in men.

Current as of: May 1, 2025

Author: Ignite Healthwise, LLC Staff

Clinical Review Board
All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.

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This information does not replace the advice of a doctor. Ignite Healthwise, LLC, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

NOTICE: This health information was not created by Columbia University Irving Medical Center and may not necessarily reflect specific CUIMC practices. For medical advice to your personal condition, please consult your doctor. Medical advice disclaimer.