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High-grade squamous intraepithelial lesions (HSIL)

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High-grade squamous intraepithelial lesions (HSIL)

High-grade squamous intraepithelial lesions (HSIL) are moderately to severely abnormal cells found on a Pap smear. These abnormal cells may point to a condition that could develop into cancer.

Current as of: May 1, 2026

Author: WebMD Ignite Staff

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This information does not replace the advice of a doctor. WebMD Ignite, disclaims any warranty or liability for your use of this information. Your use of this information means that you agree to the Terms of Use. Learn how we develop our content.

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