SEPT9 DNA test

The SEPT9 DNA test (Epi proColon) is a blood test that looks for a change in the SEPT9 gene. This gene change may be a sign of colorectal cancer. It isn't usually used as a routine screening test for people who don't have symptoms.

If the blood test doesn't find a change in the SEPT9 gene (a normal result), then you probably don't have colorectal cancer. But not all people with colorectal cancer have a change in the SEPT9 gene. So this test can't show for sure that you don't have colorectal cancer.

Current as of: May 1, 2026

Author: WebMD Ignite Staff

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