Iridocorneal Endothelial Syndrome

About Iridocorneal Endothelial Syndrome

Iridocorneal Endothelial Syndrome (ICE) is a condition that primarily creates abnormal changes in the iris (the colored part of the eye), swelling of the cornea, and the development of glaucoma, which is a disease in which normal fluid inside the eye cannot drain properly. It can cause severe vision loss. ICE is more common in women and is usually diagnosed between ages 30 to 50. It affects only one eye.


If you have ICE, there may be pain or blurry vision in one eye and noticeable changes in appearance of the iris or pupil.


A Columbia ophthalmologist will give you a comprehensive eye exam and some other testing to see if there are changes in the iris, corneal swelling, and increased pressure in the eye, which would signify glaucoma.  

Treatments We Offer

There are no current treatments that can keep ICE syndrome from developing further, but doctors can prescribe certain medications to treat the glaucoma that may be associated with ICE. A corneal transplant can also be performed to treat the corneal swelling.

Why Choose Columbia?

Columbia ophthalmologists have an incredible reputation in treating patients with corneal and outer eye diseases and disorders. Our specialists are experienced, compassionate, and thorough physicians who will make sure you are seen quickly and treated with the most advanced care.